Xseed will be bringing Akiba's Trip 2 as Akiba's Trip: Undead & Undressed to NA for both the PS3 and PSVita in summer 2014.
Here is the game's story according to the Press release:
AKIBA'S TRIP: Undead & Undressed tells the story of a young man named Nanashi who was lured into a trap and transformed into one of the walking undead. Lucky enough to be spared the worst of his fate by the kiss of a mysterious Synthister hunter named Shizuku, Nanashi is sworn to rid Akihabara of the Synthister threat. Together with the rest of his companions in an organization unofficially dubbed the "Akiba Freedom Fighters," Nanashi and Shizuku must uncover the truth behind the Synthister plague and save Akiba from being overrun by their kind.
And yes, the game will have a physical release. Xseed is looking into dual audio but for now, Japanese audio.
Here is the press release.